Le roman et des personnages dissertation

Van den vos Reynaerde was also produced as a cartoon film by Nederlandfilm in 1943. [9] The film was mostly financed with German money. While lavishly budgeted, it was never presented publicly, possibly because most Dutch Jews had already been transported to the concentration camps and the film came too late to be useful as a propaganda piece, possibly also because the Dutch collaborationist Department of People's Information, Service and Arts objected to the fact that the fox, an animal traditionally seen as "villainous", should be used as a hero. [10] In 1991, parts of the film were found again in the German Bundesarchiv . In 2005, more pieces were found, and the film has been restored. The reconstructed film was shown during the 2006 Holland Animation Film Festival in Utrecht and during the KLIK! Amsterdam Animation Festival in 2008, in the Netherlands. [11]

Obesity is a global public health problem, with about 315 million people worldwide estimated to fall into the WHO-defined obesity categories. Traditional herbal medicines may have some potential in managing obesity. Botanical dietary supplements often contain complex mixtures of phytochemicals that have additive or synergistic interactions. The dried fruit rind of Garcinia cambogia, also known as Malabar tamarind, is a unique source of (-)-hydroxycitric acid (HCA), which exhibits a distinct sour taste and has been safely used for centuries in Southeastern Asia to make meals more filling. Recently it has been demonstrated that HCA-SX or Super Citrimax, a novel derivative of HCA, is safe when taken orally and that HCA-SX is bioavailable in the human plasma as studied by GC-MS. Although HCA-SX has been observed to be conditionally effective in weight management in experimental animals as well as in humans, its mechanism of action remains to be understood. We sought to determine the effects of low-dose oral HCA-SX on the body weight and abdominal fat gene expression profile of Sprague-Dawley rats. We observed that at doses relevant for human consumption dietary HCA-SX significantly contained body weight growth. This response was associated with lowered abdominal fat leptin expression while plasma leptin levels remained unaffected. Repeated high-density microarray analysis of 9960 genes and ESTs present in the fat tissue identified a small set (approximately 1% of all genes screened) of specific genes sensitive to dietary HCA-SX. Other genes, including vital genes transcribing for mitochondrial/nuclear proteins and which are necessary for fundamental support of the tissue, were not affected by HCA-SX. Under the current experimental conditions, HCA-SX proved to be effective in restricting body weight gain in adult rats. Functional characterization of HCA-SX-sensitive genes revealed that upregulation of genes encoding serotonin receptors represent a distinct effect of dietary HCA-SX supplementation.

Le roman et des personnages dissertation

le roman et des personnages dissertation

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